Reagents developed in the Lab

Monoclonal Antibodies

Rho 1D4 monoclonal antibody    C-terminus of rhodopsin  Epitope – TETSQVAPA 

                  Applications:  Identification, purification and localization of rhodopsin in retina tissue

                                      Epitope tag:  Purification of proteins engineered   with the 1D4 C-terminal tag

                  Availability:    Large quantities:   University of British Columbia  [UBC – UILO] 
                                           Small quantities:   Millipore-Sigma,
 
 Rho 4D2 monoclonal antibody    N-terminal region of rhodopsin
                 Applications:  Identification and localization of rhodopsin in retina tissue

                 Availability:   Millipore-Sigma

 
Rim 3F4 monoclonal antibody   C-terminal region of ABCA4  Epitope –  YDLPLHPRTA
                 Applications:  Identification, purification and localization of ABCA4 in retina tissue

                                          Epitope tag:  Purification of proteins engineered with the 3F4 tag

                                          Availability:    Millipore-Sigma

 
Rim 5B4 monoclonal antibody    NBD1 region of ABCA4
                                           Applications:  Identification and localization of ABCA4 in retina tissue
                                           Availability:   Millipore-Sigma
 
 PMc 1D1 monoclonal antibody  cyclic nucleotide-gated channel A1 subunit  (CNGCA1)
                                           Applications:  Identification and localization of the cGMP-gated channel in Rod photoreceptor cells
                                           Availability:  Millipore-Sigma
 
 

Magnetic and Density Microspheres - Patents

Magnetic iron-dextran microspheres  U.S. Patent 4,452,773    Molday, R.S.

Colloidal sized metal-polysaccharide particles   U.S. Patent  4,744,760  Molday, R.S.

Metal containing polymeric functional microspheres   U.S. Patent 4,157,323  Yen, S-P. S., Rembaum, A., Molday, R.S.

Method for producing a biological reagent   U.S. Patent 4,206,094   Yen, S-P. S., Rembaum, A., Molday, R.S.

Cell specific, variable density, polymeric microspheres  U.S. Patent 4,105,598  Yen, S-P. S., Rembaum, A., Molday, R.S.

Cell sorting apparatus  U.S. Patent 4,219,411  Yen, S-P, S., Rembaum, A., Molday, R.S. 

PAX6 MiniPromoters   U.S. 10,610,56   Simpson, E., Wasserman, W., Hickmott, J., Molday, R.S.